Journal of PhytoPharmaceutical and Advanced Chemistry
Short Name: JPPAC• ISSN: 3139-9266• Peer-Reviewed Open Access
Phytochemical Profiling And Antioxidant Potential Of Calendula Officinalis: A Pharmacognostic And Biotechnological Perspective
Abstract
Calendula officinalis L. (Pot Marigold), a medicinal plant belonging to the family Asteraceae, has been widely used in traditional medicine because of its diverse therapeutic properties. Owing to its rich phytochemical composition and broad pharmacological potential, it has attracted increasing attention in herbal drug development, nutraceuticals, cosmeceuticals, and pharmaceutical biotechnology. This review aims to provide a comprehensive overview of the pharmacognostic characteristics, phytochemical profile, antioxidant potential, and biotechnological significance of C. officinalis. Relevant published literature on the pharmacognosy, phytochemistry, antioxidant activity, and medicinal plant biotechnology of C. officinalis was critically reviewed and synthesized. Information on pharmacognostic evaluation, phytochemical characterization, in vitro antioxidant assays, and biotechnological approaches was compiled and analyzed. The review indicates that C. officinalis is rich in flavonoids, phenolic compounds, carotenoids, triterpenoids, essential oils, and other bioactive metabolites responsible for its therapeutic activities. Antioxidant potential has been consistently demonstrated through assays such as DPPH radical scavenging, total phenolic content (TPC), and total flavonoid content (TFC), highlighting its ability to scavenge free radicals and regulate oxidative stress. Furthermore, pharmacognostic evaluation supports its authentication and quality assessment, while advances in plant tissue culture, metabolic engineering, and bioactive compound optimization enhance its sustainable utilization. Calendula officinalis represents a valuable natural source of antioxidants and bioactive compounds with significant potential for modern healthcare applications. Integrating pharmacognostic evaluation with biotechnological innovations can facilitate the development of standardized, effective, and sustainable herbal formulations while supporting future pharmaceutical and therapeutic applications.
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Journal of PhytoPharmaceutical and Advanced Chemistry
An international, peer-reviewed journal integrating phytopharmaceutical sciences, natural products, and advanced pharmaceutical chemistry.
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